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Given these results, the researchers conclude that there is little reason to prescribe new-generation antidepressant medications to any but the most severely depressed patients unless alternative treatments have been ineffective.
— Kirsch I, Deacon BJ, Huedo-Medina TB, Scoboria A, Moore TJ, et al. ”Initial Severity and Antidepressant Benefits: A Meta-Analysis of Data Submitted to the Food and Drug Administration.” PLoS Medicine Vol. 5, No. 2, e45 doi:10.1371/journal.pmed.0050045
